Adeno-Associated Virus (AAV), also known as Adeno-Associated viral vector, is a widely used and versatile technology in the field of gene therapy. AAV is a small, non-pathogenic virus that belongs to the family of parvoviruses. It has gained significant attention as viral vectors for delivering therapeutic genes into target cells, making it an essential component of many gene therapy treatments. AAV is also considered the safest and most effective gene delivery vehicles for gene delivery for the treatment of a variety of human diseases.

At OranssiBio, we provide AAV with the following features:

  • US/EU compliant facility with GMP and other quality requirements;
  • Fully integrated services covering process development, analytical method development, GMP manufacturing, quality control and stability testing and CMC regulatory support;

  • Scalable and highly productive serum-free suspension process with single-use bioreactors that deliver a max batch scale at 200L, suitable for multiple AAV serotypes including AAV2, AAV5, AAV6, AAV8, AAV9, and AAV10rh10, with productivities up to mid 1014 VG/L;

  • Automated and fully closed purification, sterilization, and fill/finish processes;
  • A full suite of analytical methods for in-process controls and finish product release, ensuring highest quality and safety of your product;
  • Streamline operation where in-stock pre-qualified raw materials and consumables and pre-qualified equipment to allow a rapid development of your program.

An Illustrated Flowchart for AAV

  • US/EU compliant facility with GMP and other quality requirements;
  • Fully integrated services covering process development, analytical method development, GMP manufacturing, quality control and stability testing and CMC regulatory support;

  • Scalable and highly productive serum-free suspension process with single-use bioreactors that deliver a max batch scale at 200L, suitable for multiple AAV serotypes including AAV2, AAV5, AAV6, AAV8, AAV9, and AAV10rh10, with productivities up to mid 1014 VG/L;

  • Automated and fully closed purification, sterilization, and fill/finish processes;
  • A full suite of analytical methods for in-process controls and finish product release, ensuring highest quality and safety of your product;
  • Streamline operation where in-stock pre-qualified raw materials and consumables and pre-qualified equipment to allow a rapid development of your program.